Binding & Internalisation Inhibitors

  • Compound Camostat
  • Class Binding & Internalisation Inhibitors
  • Human Studies Yes
  • FDA Approved N/A

Antiviral compounds are being investigated for their ability to interfere with the first stage of the viral life cycle, which is the attachment and entry of SARS-CoV-2.

Camostat: this is a serine protease inhibitor and camostat mesylate has been found to inhibit transmembrane protease serine 2 (TMPRSS2), which primes the spike glycoprotein of SARS-CoV-2 for entry.