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VIRAL INFECTION

Understanding virus binding to cell-surface ACE2 receptors on target cells and inhibition of spike protein-receptor interactions. Expertise in receptor binding and internalization assays.

PATHOLOGY

Investigating the pathological features associated with COVID-19 infection, focusing on the cytokine storm and multi-organ damage. Expertise in lung pathology models.

VIRAL PROTEINS & ANTIVIRALS

Exploring small molecule inhibitors of key viral proteins focusing on non-structural proteins critical for viral replication. Expertise in molecular docking and molecular dynamics simulations.

UPDATES FROM THE RESPONSE CHAMBER - LATEST NEWS

UPDATES FROM THE RESPONSE CHAMBER

Stay up-to-date with frequent news from the Response Chamber and the Broken Two of Hearts Newsletter.

SARS-CoV-2 Related Trajectories

Molecular dynamics simulations related to COVID-19.

Coronabank Chemical Collection

Collection of classical antivirals, viral binding and internalisation inhibitors, interleukin and interferon inhibitors, antibiotics, steroids and other therapeutics.

SARS-CoV-2 Related TRAJECTORIES

Small Molecules Library related to COVID-19

Coronabank Chemical Collection